Location-Dependent B-cell Function in Glioblastoma

Cancer Immunol Res. 2019 Dec;7(12):1902. doi: 10.1158/2326-6066.CIR-19-0774.

Abstract

Immunotherapy has shown remarkable successes in several tumor types and is now the first-line treatment for several conditions, including recurring disease. Nonetheless, a large fraction of patients does not respond, which is particularly true in glioblastoma. The results of Lee-Chang and colleagues point to intratumoral B cells as a potential target for immunotherapy.See article by Lee-Chang et al., p. 1928.

Publication types

  • Comment

MeSH terms

  • B-Lymphocytes
  • Glioblastoma*
  • Humans
  • Immunotherapy
  • Neoplasm Recurrence, Local