1 Department of Biotechnology, Chemistry and Pharmacy, Department of Excellence 2018-2022 , University of Siena , via Aldo Moro 2 , 53100 Siena , Italy.
2 Department of Chemistry and Technology of Drugs, Department of Excellence 2018-2022 , Sapienza University of Rome , Piazzale Aldo Moro 5 , 00185 Rome , Italy.