Abstract
2019 saw advances in the generation of induced pluripotent stem cell (iPSC)-derived nephron progenitors and in our understanding of how nephrons form in a kidney organoid. Fundamental studies of regeneration in zebra fish continue to provide vital clues as to how we might use iPSC-derived cells to regenerate a human nephron in vivo.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Cell Differentiation / physiology*
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Humans
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Induced Pluripotent Stem Cells / cytology
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Induced Pluripotent Stem Cells / physiology*
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Nephrons / embryology*
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Nephrons / physiology
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Organogenesis / physiology*
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Organoids
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Regeneration / physiology*
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Stem Cells
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Zebrafish