Weil syndrome causing autoimmune haemolytic anaemia

Natl Med J India. 2019 Mar-Apr;32(2):88-89. doi: 10.4103/0970-258X.275913.

Abstract

Weil syndrome is a fulminant form of leptospirosis, usually caused by spirochetal organism Leptospira interrogans. It is characterized by icterus, petechial rashes over the body, signs of renal failure and hepatic failure. Anaemia is a usual manifes- tation of Leptospira infection, but autoimmune haemolytic anaemia is rare. We report a patient with autoimmune haemolytic anaemia following Leptospira infection, which was responsive to high-dose steroid therapy.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Hemolytic, Autoimmune / blood
  • Anemia, Hemolytic, Autoimmune / diagnosis
  • Anemia, Hemolytic, Autoimmune / drug therapy
  • Anemia, Hemolytic, Autoimmune / immunology*
  • Anti-Bacterial Agents / therapeutic use
  • Antibodies, Bacterial / blood
  • Antibodies, Bacterial / immunology*
  • Drug Therapy, Combination / methods
  • Glucocorticoids / administration & dosage
  • Hemoglobins / analysis
  • Humans
  • Immunoglobulin M / blood
  • Immunoglobulin M / immunology*
  • Leptospira interrogans / immunology*
  • Leptospira interrogans / isolation & purification
  • Male
  • Middle Aged
  • Treatment Outcome
  • Weil Disease / complications*
  • Weil Disease / diagnosis
  • Weil Disease / drug therapy
  • Weil Disease / microbiology

Substances

  • Anti-Bacterial Agents
  • Antibodies, Bacterial
  • Glucocorticoids
  • Hemoglobins
  • Immunoglobulin M