[Acute autoimmune myocarditis secondary to Graves' disease: a case report]

Rev Med Interne. 2020 Mar;41(3):206-209. doi: 10.1016/j.revmed.2019.12.017. Epub 2020 Jan 22.
[Article in French]

Abstract

Introduction: Interactions between heart and thyroid are strong. Main cardiac complications of Graves' disease are supra-ventricular tachycardia or high output cardiac failure, without real myocardial involvement.

Observation: A 40-year-old man with history of refractory Graves' disease was hospitalized for an acute chest pain with elevated cardiac biomarkers and normal coronarography. Acute myocarditis was confirmed by cardiac MRI. We found no evidence for an infectious etiology. We retained the hypothesis of acute autoimmune myocarditis in the context of active Graves' disease.

Conclusion: Acute myocarditis is an exceptional complication of Graves' disease, with most likely an autoimmune mechanism. Possible occurrence of fulminant rhythmic or hemodynamic complications justify minimal cardiological check-up before introducing beta blockers.

Keywords: Auto-immunité; Autoimmunity; Chest pain; Douleur thoracique; Graves’ disease; Maladie de Basedow; Myocardite; Myocarditis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Autoimmune Diseases / diagnosis
  • Autoimmune Diseases / etiology*
  • Chest Pain / diagnosis
  • Chest Pain / etiology
  • Graves Disease / complications*
  • Graves Disease / diagnosis
  • Graves Disease / immunology
  • Humans
  • Male
  • Myocarditis / diagnosis
  • Myocarditis / etiology*
  • Myocarditis / immunology