Steady State Concentration

Excerpt

Pharmacokinetics (PK) describes the mathematical relationship between the dose of the drug administered and its measured concentration at an easily accessible site of the body. PK, in particular, is a study of what the body does to a drug, deals with the processes of absorption, distribution, metabolism, and elimination (acronym ADME). Within the PK, the steady-state is a concept of fundamental importance in pharmacology. It describes a dynamic equilibrium in which drug concentrations consistently stay within therapeutic limits for long, potentially indefinite, periods. The concentration around which the drug concentration consistently stays is known as the steady-state concentration.