A curious finding of skin blebs: A case report

Indian J Pharmacol. 2019 Nov-Dec;51(6):407-409. doi: 10.4103/ijp.IJP_288_19. Epub 2020 Jan 16.

Abstract

Mannitol has been the cornerstone of osmotherapy in the treatment of raised intracranial pressure for the past several decades. We discuss here a case of subcutaneous mannitol extravasation, leading to bullous eruptions and swelling in the forearm of a postoperative patient of arteriovenous malformation. We emphasize the importance of careful selection of peripheral intravenous catheter site, especially when infusing hypertonic solutions with propensity for subcutaneous leaks and tissue damage.

Keywords: Bullous eruptions; extravasation; mannitol.

Publication types

  • Case Reports

MeSH terms

  • Blister / chemically induced*
  • Catheterization
  • Child
  • Female
  • Humans
  • Infusions, Intravenous
  • Intracranial Hypertension / drug therapy*
  • Mannitol / administration & dosage
  • Mannitol / adverse effects*
  • Natriuretic Agents / administration & dosage
  • Natriuretic Agents / adverse effects*

Substances

  • Natriuretic Agents
  • Mannitol