Moving proteins along in the cilium

Elife. 2020 Feb 13:9:e55254. doi: 10.7554/eLife.55254.

Abstract

The structures of the bovine and human BBSome reveal that a conformational change is required to recruit the complex to the ciliary membrane.

Keywords: BBSome; arl6; bos taurus; cilia; cryo-em; human; intraflagellar transport; molecular biophysics; structural biology.

Publication types

  • Comment

MeSH terms

  • Animals
  • Bardet-Biedl Syndrome* / metabolism
  • Cattle
  • Cell Movement
  • Cilia* / metabolism
  • Humans
  • Membrane Proteins / metabolism
  • Protein Transport

Substances

  • Membrane Proteins