Non-prescription medicines may contribute to non-adherence to prescription medicines in people living with chronic health conditions

Int J Clin Pract. 2020 Jun;74(6):e13489. doi: 10.1111/ijcp.13489. Epub 2020 Mar 4.

Abstract

Background: Non-adherence to prescribed medicines is linked to adverse health outcomes in people living with chronic health conditions (CHCs). Multiple factors are known to contribute to non-adherence to medicines including polypharmacy, demographic features and disease and health systems. Both non-prescription and prescription medicines contribute to polypharmacy; however, there is limited data on the influence of non-prescription medicines to non-adherence.

Aim: Therefore, the aim of the study was to investigate the influence of non-prescription medicines to non-adherence in an Australian population.

Methods: Data from the 2016 National Survey of a random sample of Australian adult residents were utilised in this study to investigate factors associated with non-adherence. Descriptive statistics, χ2 , regression and generalised linear models were used to assess the relationships between variables of interest. Narrative response and comments were used to provide further insight.

Results: This study recruited 1217 participants to explore factors associated with non-adherence to medicines. Weak but statistically significant correlations were identified showing the number of CHCs, patient's age, number of prescription medicines, number of non-prescription medicines and total number of medicines associated with non-adherence.

Discussion: The findings suggest that people living with CHCs and taking multiple medicines, including non-prescription medicines, are likely to be non-adherent to prescription medicines. This study shows the possible involvement of non-prescription medicines in contributing to non-adherence in an Australian population and suggests that future studies with a broader demographic are warranted.

MeSH terms

  • Adult
  • Aged
  • Australia
  • Chronic Disease / drug therapy*
  • Chronic Disease / psychology
  • Female
  • Humans
  • Male
  • Medication Adherence / psychology
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Nonprescription Drugs / therapeutic use*
  • Polypharmacy*
  • Prescription Drugs / adverse effects
  • Prescription Drugs / therapeutic use*

Substances

  • Nonprescription Drugs
  • Prescription Drugs