Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides are a heterogeneous group of rare autoimmune conditions that cause inflammation of blood vessels with various manifestations. This group includes 3 main diseases—granulomatosis with polyangiitis (GPA), formerly known as Wegener granulomatosis; eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss syndrome; and microscopic polyangiitis (MPA). Other ANCA-associated diseases include drug-induced vasculitis and renal-limited vasculitis.
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