Effectiveness of clozapine, oxcarbazepine and rivastigmine combination in a bipolar disorder patient with initial cerebral atrophy

Paolo Morana; Federico Mucci; Stefano Baroni; Alessandra Della Vecchia; Armando Piccinni; Benedetto Morana; Donatella Marazziti

doi:10.1002/ccr3.2462

Effectiveness of clozapine, oxcarbazepine and rivastigmine combination in a bipolar disorder patient with initial cerebral atrophy

Clin Case Rep. 2020 Jan 7;8(2):254-257. doi: 10.1002/ccr3.2462. eCollection 2020 Feb.

Authors

Paolo Morana¹, Federico Mucci², Stefano Baroni², Alessandra Della Vecchia², Armando Piccinni^{3

4}, Benedetto Morana¹, Donatella Marazziti^{2

3

4}

Affiliations

¹ Casa di cura Morana Marsala Italy.
² Dipartimento di Medicina Clinica e Sperimentale Section of Psychiatry University of Pisa Italy.
³ Brain Research Foundation (BRF) Lucca Italy.
⁴ UNICamillus University of health medical sciences Roma Italy.

Abstract

This paper reports the case of a 46-year-old woman suffering from bipolar disorder of type I with mixed features with initial fronto-temporal atrophy. Although considered treatment-resistant to conventional strategies, she successfully responded to a combination of rivastigmine, clozapine, and oxcarbazepine.

Keywords: bipolar disorders; clozapine; depression; fronto‐temporal atrophy; mixed features; oxcarbazepine; rivastigmine.

Publication types

Case Reports