Genome Sequence of a Segmented Filamentous Bacterium Strain That Confers a Rotavirus Resistance Phenotype in Mice

Zhenda Shi; Chunyu Zhao; Lisa M Mattei; Kyle Bittinger; Baoming Jiang; Andrew T Gewirtz

doi:10.1128/MRA.00073-20

Genome Sequence of a Segmented Filamentous Bacterium Strain That Confers a Rotavirus Resistance Phenotype in Mice

Microbiol Resour Announc. 2020 Mar 5;9(10):e00073-20. doi: 10.1128/MRA.00073-20.

Authors

Zhenda Shi¹, Chunyu Zhao², Lisa M Mattei², Kyle Bittinger², Baoming Jiang³, Andrew T Gewirtz⁴

Affiliations

¹ Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA.
² Gastroenterology, Hepatology, and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
³ Gastroenteritis and Respiratory Viruses Laboratory Branch, Division of Viral Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
⁴ Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA agewirtz@gsu.edu.

Abstract

Segmented filamentous bacteria (SFB) are well appreciated for eliciting Th17 cell immune responses. Here, we report the genome sequence of a murine isolate of SFB, which confers strong protection against rotavirus infection independent of acquired immunity.

Abstract

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