Comparison of process outcomes, clinical symptoms and laboratory values between patients with antepartum preeclampsia, antepartum with persistent postpartum preeclampsia, and new onset postpartum preeclampsia

J Gynecol Obstet Hum Reprod. 2020 May;49(5):101724. doi: 10.1016/j.jogoh.2020.101724. Epub 2020 Mar 12.

Abstract

Objective: There is limited literature on postpartum preeclampsia for process outcomes, clinical symptoms, and laboratory values.

Method: Retrospective study comparing 3 groups of antepartum preeclampsia without postpartum preeclampsia (APNP; n = 43), antepartum preeclampsia with persistent postpartum preeclampsia (APYP; n = 59), and new onset postpartum preeclampsia (NEWYP; n = 18).

Results: For process outcomes, NEWYP had higher odds for readmission as compared to APYP [OR: 5.41, 95 % CI: 1.34, 21.56, p = 0.02]. For clinical symptoms of postpartum highest systolic blood pressure NEWYP had greater values as compared to both APYP [B = 19.95, SE = 3.84, p < 0.001] and APNP [B = 23.63, SE = 2.87, p < 0.001]. For laboratory values of serum creatinine, NEWYP had greater values as compared to both APYP [B = 0.15, SE = 0.05, p = 0.01] and APNP [B = 0.17, SE = 0.05, p = 0.002].

Conclusion: NEWYP may represent a different disorder from APNP and APYP. We recommend close monitoring of NEWYP by clinicians.

Keywords: Magnesium sulfate; Patient readmission; Postpartum period; Preeclampsia.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Blood Pressure
  • Body Mass Index
  • Female
  • Gestational Age
  • Humans
  • Magnesium Sulfate / administration & dosage
  • Patient Readmission / statistics & numerical data
  • Pre-Eclampsia / diagnosis*
  • Pre-Eclampsia / epidemiology
  • Pre-Eclampsia / physiopathology
  • Pregnancy
  • Pregnancy Outcome
  • Puerperal Disorders / diagnosis*
  • Puerperal Disorders / epidemiology
  • Puerperal Disorders / physiopathology
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome

Substances

  • Magnesium Sulfate