Low Cost Screening for Features of Prodromal Parkinson's Disease in General Medical Practice in Italy

J Parkinsons Dis. 2020;10(2):711-715. doi: 10.3233/JPD-191868.

Abstract

The aim of the study was to determine the feasibility of screening older adults attending general medical practice for features suggesting prodromal Parkinson's disease (PD). Four general practitioners recruited 392 subjects aged ≥60 years, attending their primary clinics. A self-administered questionnaire collected information on history of probable rapid eye movements sleep behavior disorder (pRBD), constipation, risk markers for PD, and on subjective cognitive function. Olfactory function was tested. Constipation (27.8%), and hyposmia (19.9%), but not pRBD (4.3%), were more prevalent with age. Further supporting the feasibility of a longitudinal study, 299 subjects agreed to be followed.

Keywords: Parkinson’s disease; epidemiology; health policy and practice.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Cognitive Dysfunction / diagnosis*
  • Cognitive Dysfunction / epidemiology
  • Cognitive Dysfunction / etiology
  • Constipation / diagnosis*
  • Constipation / epidemiology
  • Constipation / etiology
  • Diagnostic Self Evaluation
  • Early Diagnosis
  • Feasibility Studies
  • Female
  • General Practice / economics*
  • Health Policy / economics
  • Humans
  • Italy / epidemiology
  • Male
  • Middle Aged
  • Olfaction Disorders / diagnosis*
  • Olfaction Disorders / epidemiology
  • Olfaction Disorders / etiology
  • Parkinson Disease / complications
  • Parkinson Disease / diagnosis*
  • Parkinson Disease / epidemiology
  • Prevalence
  • Prodromal Symptoms*
  • REM Sleep Behavior Disorder / diagnosis*
  • REM Sleep Behavior Disorder / epidemiology
  • REM Sleep Behavior Disorder / etiology