Detection of serum IgM and IgG for COVID-19 diagnosis

Ling Zhong; Junlan Chuan; Bo Gong; Ping Shuai; Yu Zhou; Yi Zhang; Zhilin Jiang; Dingding Zhang; Xiaoqi Liu; Shi Ma; Yi Huang; He Lin; Qingwei Wang; Lulin Huang; Dan Jiang; Fang Hao; Juan Tang; Chunqi Zheng; Hua Yu; Zhibin Wang; Qi Jiang; Tao Zeng; Mei Luo; Fanwei Zeng; Fanxin Zeng; Jianghai Liu; Junxi Tian; Yu Xu; Tengxiang Long; Kaiju Xu; Xingxiang Yang; Yuping Liu; Yi Shi; Li Jiang; Zhenglin Yang

doi:10.1007/s11427-020-1688-9

Detection of serum IgM and IgG for COVID-19 diagnosis

Sci China Life Sci. 2020 May;63(5):777-780. doi: 10.1007/s11427-020-1688-9. Epub 2020 Mar 25.

Authors

Ling Zhong^{1

2

3}, Junlan Chuan^{1

2}, Bo Gong^{1

2

3}, Ping Shuai⁴, Yu Zhou^{1

2

3}, Yi Zhang^{1

2

3}, Zhilin Jiang^{1

2

3}, Dingding Zhang^{1

2

3}, Xiaoqi Liu^{1

2

3}, Shi Ma^{1

2

3}, Yi Huang¹, He Lin^{1

2

3}, Qingwei Wang^{1

2

3}, Lulin Huang^{1

2

3}, Dan Jiang^{1

2

3}, Fang Hao^{1

2

3}, Juan Tang⁵, Chunqi Zheng⁵, Hua Yu¹, Zhibin Wang¹, Qi Jiang⁶, Tao Zeng⁷, Mei Luo⁷, Fanwei Zeng⁸, Fanxin Zeng⁸, Jianghai Liu⁹, Junxi Tian¹⁰, Yu Xu¹⁰, Tengxiang Long¹⁰, Kaiju Xu¹¹, Xingxiang Yang¹¹, Yuping Liu⁴, Yi Shi^{12

13

14}, Li Jiang^{15

16

17}, Zhenglin Yang^{18

19

20}

Affiliations

¹ The Key Laboratory for Human Disease Gene Study of Sichuan Province and Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
² Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences, Chengdu, 610072, China.
³ Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, 610072, China.
⁴ Health Management Center, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China.
⁵ Infectious Disease Department, Zigong first people's Hospital, Zigong, 643000, China.
⁶ Sichuan Mianyang 404 Hospital, Mianyang, 621000, China.
⁷ Infectious Diseases Laboratory, Public Health and Clinical Center of Chengdu, Chengdu, 610041, China.
⁸ Sichuan Dazhou Central Hosptical, Dazhou, 635000, China.
⁹ ABLINK Biotech, Chengdu, 610041, China.
¹⁰ Maccura Biotechnology Co., Ltd., Chengdu, 610041, China.
¹¹ Infectious Disease Department, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610041, China.
¹² The Key Laboratory for Human Disease Gene Study of Sichuan Province and Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. shiyi1614@126.com.
¹³ Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences, Chengdu, 610072, China. shiyi1614@126.com.
¹⁴ Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, 610072, China. shiyi1614@126.com.
¹⁵ The Key Laboratory for Human Disease Gene Study of Sichuan Province and Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. jiang.li@hsc.utah.edu.
¹⁶ Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences, Chengdu, 610072, China. jiang.li@hsc.utah.edu.
¹⁷ Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, 610072, China. jiang.li@hsc.utah.edu.
¹⁸ The Key Laboratory for Human Disease Gene Study of Sichuan Province and Institute of Laboratory Medicine, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, China. zliny@yahoo.com.
¹⁹ Research Unit for Blindness Prevention of Chinese Academy of Medical Sciences (2019RU026), Sichuan Academy of Medical Sciences, Chengdu, 610072, China. zliny@yahoo.com.
²⁰ Natural Products Research Center, Institute of Chengdu Biology, Sichuan Translational Medicine Hospital, Chinese Academy of Sciences, Chengdu, 610072, China. zliny@yahoo.com.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Viral / blood
Antibodies, Viral / immunology
Betacoronavirus / immunology*
COVID-19
COVID-19 Testing
Clinical Laboratory Techniques*
Coronavirus Infections / blood
Coronavirus Infections / diagnosis*
Coronavirus Infections / immunology
Enzyme-Linked Immunosorbent Assay
Humans
Immunoglobulin G / blood
Immunoglobulin M / blood
Pandemics
Pneumonia, Viral / blood
Pneumonia, Viral / diagnosis*
Pneumonia, Viral / immunology
SARS-CoV-2

Substances

Antibodies, Viral
Immunoglobulin G
Immunoglobulin M