An Overview of the Current State and the Future of Ataxia Treatments

Neurol Clin. 2020 May;38(2):449-467. doi: 10.1016/j.ncl.2020.01.008. Epub 2020 Feb 27.

Abstract

Cerebellar ataxia can be caused by a variety of disorders, including degenerative processes, autoimmune and paraneoplastic illness as well as by gene mutations inherited in autosomal dominant, autosomal recessive, or X-linked fashions. In this review, we highlight the treatments for cerebellar ataxia in a systematic way, to provide guidance for clinicians who treat patients with cerebellar ataxia. In addition, we review therapies currently under development for ataxia, which we feel is currently one of the most exciting fields in neurology.

Keywords: Ataxia; Ataxia treatment; Cerebellum; Friedreich ataxia; Multiple system atrophy; Spinocerebellar ataxia.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cerebellar Ataxia / therapy*
  • Humans