Engineering of Laccase CueO for Improved Electron Transfer in Bioelectrocatalysis by Semi-Rational Design

Lingling Zhang; Haiyang Cui; Gaurao V Dhoke; Zhi Zou; Daniel F Sauer; Mehdi D Davari; Ulrich Schwaneberg

doi:10.1002/chem.202001027

Engineering of Laccase CueO for Improved Electron Transfer in Bioelectrocatalysis by Semi-Rational Design

Chemistry. 2020 Apr 16;26(22):4884. doi: 10.1002/chem.202001027.

Authors

Lingling Zhang¹, Haiyang Cui¹, Gaurao V Dhoke¹, Zhi Zou^{1

2}, Daniel F Sauer¹, Mehdi D Davari¹, Ulrich Schwaneberg^{1

2}

Affiliations

¹ Institute of Biotechnology, RWTH Aachen University, Worringer Weg 3, 52074, Aachen, Germany), E-mail: u.
² DWI Leibniz-Institute for Interactive Materials, Forckenbeckstrasse 50, 52074, Aachen, Germany.

PMID: 32297426
DOI: 10.1002/chem.202001027

Abstract

Invited for the cover of this issue is the group of Ulrich Schwaneberg at the Institute of Biotechnology, RWTH-Aachen University and DWI Lebniz Institute of Interactive Materials. The picture calls for special attention to be paid to the extra Cu binding site of Copper efflux Oxidase (CueO), due to its predominant function in tuning the electrocatalytic kinetics towards oxygen reduction. Read the full text of the article at 10.1002/chem.201905598.

MeSH terms

Binding Sites
Ceruloplasmin / chemistry
Ceruloplasmin / metabolism*
Electron Transport
Escherichia coli Proteins / chemistry
Kinetics
Laccase / chemistry*
Oxidation-Reduction
Oxidoreductases / chemistry*
Oxidoreductases / metabolism

Substances

Escherichia coli Proteins
Oxidoreductases
Laccase
copper oxidase
Ceruloplasmin