N6-methyladenine is incorporated into mammalian genome by DNA polymerase

Cell Res. 2021 Jan;31(1):94-97. doi: 10.1038/s41422-020-0317-6. Epub 2020 Apr 30.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenine / analogs & derivatives*
  • Adenine / analysis
  • Adenine / metabolism
  • AlkB Homolog 1, Histone H2a Dioxygenase / deficiency
  • AlkB Homolog 1, Histone H2a Dioxygenase / genetics
  • Cell Line
  • Chromatography, High Pressure Liquid
  • DNA-Directed DNA Polymerase / metabolism*
  • Deoxyadenosines / chemistry
  • Genome, Human / genetics*
  • Humans
  • Isotope Labeling
  • Tandem Mass Spectrometry

Substances

  • Deoxyadenosines
  • ALKBH1 protein, human
  • AlkB Homolog 1, Histone H2a Dioxygenase
  • DNA-Directed DNA Polymerase
  • Adenine
  • 2'-deoxyadenosine
  • 6-methyladenine