Characterization of the novel HLA-DQB1*03:01:46 variant allele in a French hematopoietic stem cell donor

HLA. 2020 Sep;96(3):370-371. doi: 10.1111/tan.13921. Epub 2020 Jun 10.

Authors

Céline Dard¹, Ornella Senoussi¹, Sylvie Ferrari-Lacraz², Béatrice Bardy¹, Dominique Masson¹

Affiliations

¹ Department of Biology and Therapies, Histocompatibility Laboratory, Etablissement Français du sang Auvergne-Rhône-Alpes, Grenoble, France.
² Transplantation Immunology Unit and National Reference Laboratory for Histocompatibility, Department of Diagnostic, Geneva University Hospitals, Geneva, Switzerland.

PMID: 32367655
DOI: 10.1111/tan.13921

Abstract

HLA-DQB1*03:01:46 differs from HLA-DQB1*03:01:01:01 by one nucleotide substitution at codon 142.3 in exon 3.

Keywords: HLA-DQB1*03:01:46; NGS; human leucocyte antigen; novel HLA alleles.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Publication types

Case Reports

MeSH terms

Alleles
Base Sequence
HLA-DQ beta-Chains / genetics
Hematopoietic Stem Cells*
Histocompatibility Testing

Substances

HLA-DQ beta-Chains
HLA-DQB1 antigen