Natural History of Mixed and Motor Nerve Cryoablation in Humans-A Cohort Analysis

J Vasc Interv Radiol. 2020 Jun;31(6):912-916.e1. doi: 10.1016/j.jvir.2019.11.026. Epub 2020 May 4.

Abstract

Eight patients who underwent percutaneous cryoablation of mixed and/or motor nerves over a period of 5 years were identified. Distances from the ablation sites to origins of distal musculature were measured, and times to initial clinical recovery were collected. Strength progression over time following muscle activation was also collected and analyzed. All patients demonstrated activation of all muscles distal to the ablation, and the calculated mean rate of nerve regeneration based on distance to the origin of the assessed musculature and time to muscle activation for the group was 1.5 mm/day ± 1.1.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Cryosurgery* / adverse effects
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motor Neurons / pathology
  • Muscle Denervation / adverse effects
  • Muscle Denervation / methods*
  • Muscle Strength*
  • Muscle, Skeletal / innervation*
  • Nerve Regeneration*
  • Pain / diagnosis
  • Pain / physiopathology
  • Pain / surgery*
  • Peripheral Nerve Injuries / diagnosis
  • Peripheral Nerve Injuries / etiology
  • Peripheral Nerve Injuries / pathology
  • Peripheral Nerve Injuries / physiopathology*
  • Peripheral Nerves / pathology
  • Peripheral Nerves / physiopathology
  • Peripheral Nerves / surgery*
  • Prospective Studies
  • Recovery of Function
  • Time Factors
  • Treatment Outcome
  • Young Adult