Inferior vena cava filters do not increase the risk of blood stream infections in patients with newly diagnosed VTE

Am J Infect Control. 2020 Dec;48(12):1491-1496. doi: 10.1016/j.ajic.2020.05.029. Epub 2020 May 30.

Abstract

Background: The association between inferior vena cava (IVC) filter presence and subsequent bloodstream infection (BSI) is unknown. We hypothesized among patients with a new diagnosis of venous thromboembolism (VTE), incidence of BSI after 1 year would be higher in patients who had presence of an IVC filter.

Methods: We performed a retrospective cohort study of patients with newly diagnosed VTE but no IVC filter (N = 4,053) and patients with IVC filter (N = 635) admitted to a metropolitan hospital system from 2006 to 2009 comparing incidence of BSI within 1 year of inclusion. Multivariable regression modeling was used to evaluate the association of IVC filter placement with BSI 1 year after placement.

Results: Patients with an IVC filter placed were more likely to be older with higher Charlson co-morbidity score (median 4 vs 1; P < .001). The incidence of BSI was not different between the group with IVC filter and the group without (10.7% vs 8.8%; P = .12). There was no association with IVC filter placement and BSI before or after multivariable adjustment.

Conclusions: In patients newly diagnosed with VTE, we found no association between IVC filter placement and increased incidence of BSI after 1 year.

Keywords: Bacteremia; Deep vein thrombosis; IVC; Inferior vena cava filter; Venous thromboembolism.

MeSH terms

  • Humans
  • Pulmonary Embolism*
  • Retrospective Studies
  • Risk Factors
  • Treatment Outcome
  • Vena Cava Filters* / adverse effects
  • Venous Thromboembolism* / epidemiology
  • Venous Thromboembolism* / etiology