Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19)

Jenna S Silverstein; Meghana A Limaye; Sara G Brubaker; Ashley S Roman; Judita Bautista; Judith Chervenak; Adam J Ratner; Philip M Sommer; Nicole M Roselli; Charlisa D Gibson; David Ellenberg; Christina A Penfield

doi:10.1055/s-0040-1712925

Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19)

AJP Rep. 2020 Apr;10(2):e169-e175. doi: 10.1055/s-0040-1712925. Epub 2020 Jun 4.

Authors

Jenna S Silverstein^{1

2}, Meghana A Limaye^{3

4}, Sara G Brubaker^{3

4}, Ashley S Roman³, Judita Bautista^{1

2}, Judith Chervenak^{3

4}, Adam J Ratner⁵, Philip M Sommer⁶, Nicole M Roselli^{1

2}, Charlisa D Gibson⁷, David Ellenberg⁷, Christina A Penfield^{3

4}

Affiliations

¹ Department of Obstetrics and Gynecology, New York University Langone Medical Center, New York, New York.
² Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York, New York.
³ Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, New York University Langone Medical Center, New York, New York.
⁴ Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Bellevue Hospital Center, New York, New York.
⁵ Division of Pediatric Infectious Diseases, Department of Pediatrics, Hassenfeld Children's Hospital at New York University Langone Medical Center, New York, New York.
⁶ Department of Anesthesiology and Critical Care Medicine, New York University Langone Medical Center, New York, New York.
⁷ Division of Pulmonary and Critical Care, Department of Internal Medicine, New York University Langone Medical Center, New York, New York.

Abstract

There is a current paucity of information about the obstetric and perinatal outcomes of pregnant novel coronavirus disease 2019 (COVID-19) patients in North America. Data from China suggest that pregnant women with COVID-19 have favorable maternal and neonatal outcomes, with rare cases of critical illness or respiratory compromise. However, we report two cases of pregnant women diagnosed with COVID-19 in the late preterm period admitted to tertiary care hospitals in New York City for respiratory indications. After presenting with mild symptoms, both quickly developed worsening respiratory distress requiring intubation, and both delivered preterm via caesarean delivery. These cases highlight the potential for rapid respiratory decompensation in pregnant COVID-19 patients and the maternal-fetal considerations in managing these cases.

Keywords: COVID-19; SARS-CoV-2; critical illness; intubation; pregnancy.

Publication types

Case Reports

Grants and funding

Funding No financial support was received for this case report. IRB exemption status was received for this report.