Disseminated invasive aspergillosis in patients with severe influenza infection

Grégoire Monseau; Mathilde Wairy; Marie Flores; Kevin Brunet; Faustine Reynaud; Damien Marie; Florence Boissier; Delphine Chatellier; Anne Veinstein; Jean-Pierre Frat; René Robert; Arnaud W Thille

doi:10.1016/j.idcr.2020.e00777

Disseminated invasive aspergillosis in patients with severe influenza infection

IDCases. 2020 May 11:20:e00777. doi: 10.1016/j.idcr.2020.e00777. eCollection 2020.

Authors

Affiliations

¹ CHU de Poitiers, Service de Médecine Intensive et Réanimation, Poitiers, France.
² CHU de Poitiers, Service d'Anatomo-pathologie, Poitiers, France.
³ CHU de Poitiers, Laboratoire de Parasitologie et Mycologie Médicale, Poitiers, France.
⁴ INSERM CIC 1402 ALIVE, Université de Poitiers, Poitiers, France.

Abstract

A female 66 year-old patient, not immunocompromised, was admitted in ICU for severe influenza complicated by severe acute respiratory distress syndrome (ARDS) leading to extra-corporeal membrane oxygenation (ECMO). During ICU hospitalization, she developed a disseminated invasive aspergillosis with cerebral access and coronary occlusion which lead to cardiac arrest. Despite a successful revascularization procedure, the patient died of refractory shock.