Histological and prognostic data on surgically resected early-stage lung adenocarcinoma

Masaya Yotsukura; Hisao Asamura; Shigeki Suzuki; Keisuke Asakura; Yukihiro Yoshida; Kazuo Nakagawa; Hiroyuki Sakurai; Shun-Ichi Watanabe; Noriko Motoi

doi:10.1016/j.dib.2020.105785

Histological and prognostic data on surgically resected early-stage lung adenocarcinoma

Data Brief. 2020 May 29:31:105785. doi: 10.1016/j.dib.2020.105785. eCollection 2020 Aug.

Authors

Masaya Yotsukura^{1

2

3}, Hisao Asamura³, Shigeki Suzuki⁴, Keisuke Asakura³, Yukihiro Yoshida², Kazuo Nakagawa², Hiroyuki Sakurai⁵, Shun-Ichi Watanabe², Noriko Motoi^{1

6}

Affiliations

¹ Department of Pathology and Clinical Laboratories, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
² Department of Thoracic Surgery, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.
³ Division of Thoracic Surgery, Keio University School of Medicine, 35, Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
⁴ Department of Thoracic Surgery, Sagamihara Kyodo Hospital, 2-8-18, Hashimoto, Midori-ku, Sagamihara, Kanagawa Prefecture 252-5188, Japan.
⁵ Division of Respiratory Surgery, Nihon University School of Medicine, 30-1 Oyaguchikamimachi, Itabashi-ku, Tokyo 173-8610, Japan.
⁶ Department of Diagnostic Pathology, National Cancer Center Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

Abstract

This article presents supplementary data for the research article by Yotsukura et al. entitled "Prognostic impact of cancer-associated active fibroblasts and invasive architectural patterns on early-stage lung adenocarcinoma" [1], which presented the postoperative prognosis for early-stage lung adenocarcinoma categorized according to histological findings. We included data of 1,032 resected cases of lung adenocarcinoma, which consisted of pathological stage IA invasive cancer and adenocarcinoma in situ resected at National Cancer Center Hospital, Tokyo, Japan, between 2007 and 2012. A pathological review was performed to assess total tumor size, size of invasion, histological subtype, lymphovascular invasion, and presence of cancer-associated active fibroblast (CAF). Tumor recurrence and overall survival were retrospectively recorded. Of the included cases, 166 (16.1%), and 866 (83.9%) were adenocarcinoma in situ and pathological stage IA, respectively. Pathological stage IA adenocarcinoma was further classified based on the histologial subtype and the presence of CAF. This data set may be useful for analyzing the postoperative prognosis of early-stage lung adenocarcinoma, in combination with detailed pathological findings including size of invasion, histological subtype, and presence of CAF.

Keywords: Lung adenocarcinoma; cancer-associated active fibroblast; histological subtype; recurrence.