"Dysmorphic" lysosomes in proximal tubular cells are not specific for CINAC/CKDu and do not provide evidence that CINAC/CKDu is a toxin-induced disease
Kidney Int. 2020 Sep;98(3):786-787.
doi: 10.1016/j.kint.2020.04.057.
Epub 2020 Jun 18.
1 Department of Clinical Science, Intervention and Technology, Division of Renal Medicine, Karolinska Institutet, Stockholm, Sweden.
2 Department of Laboratory Medicine, Division of Clinical Research Centre, Karolinska Institutet, Stockholm, Sweden.
3 Cardiovascular, Renal and Metabolism Safety, Clinical Pharmacology and Safety Sciences, AstraZeneca R&D, Gothenburg, Sweden; Clinical Pathology/Cytology Department, Karolinska University Hospital, Stockholm, Sweden.
4 Department of Clinical Science, Intervention and Technology, Division of Renal Medicine, Karolinska Institutet, Stockholm, Sweden; Clinical Pathology/Cytology Department, Karolinska University Hospital, Stockholm, Sweden. Electronic address: annika.wernerson@ki.se.