Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis

Hemasphere. 2020 May 27;4(3):e356. doi: 10.1097/HS9.0000000000000356. eCollection 2020 Jun.

Nikolaos Sousos^{1

2}, Gemma Buck¹, Alba Rodriguez-Meira¹, Ruggiero Norfo¹, Angela Hamblin^{2

3

4}, Francesco Pezzella⁵, Jennifer Davies⁶, Philip Hublitz⁷, Bethan Psaila^{1

2

4}, Adam J Mead^{1

2

4}

¹ MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
² Cancer and Haematology Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
³ Oxford Molecular Diagnostics Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
⁴ National Institute for Health Research Biomedical Research Centre, Oxford, UK.
⁵ Cellular Pathology Clinical Service Unit - Haematopathology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
⁶ Haematology Department, Wycombe Hospital, Buckinghamshire Healthcare NHS Trust, High Wycombe, UK.
⁷ Genome Engineering Facility, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Abstract