Genome characterization of brugmansia latent virus, a novel tobamovirus

Arch Virol. 2020 Oct;165(10):2389-2392. doi: 10.1007/s00705-020-04718-z. Epub 2020 Jul 22.

Abstract

A novel tobamovirus, brugmansia latent virus (BrLV), was discovered during a study of brugmansia (Brugmansia spp.) in the living collections held at the Royal Botanic Gardens, Kew. Here, we report the complete genome sequence of BrLV, which is 6,397 nucleotides long and contains the four open reading frames (RNA-dependent RNA polymerase, methyltransferase/helicase, movement, and coat proteins) typical of tobamoviruses. The complete genome sequence of BrLV shares 69.7% nucleotide sequence identity with brugmansia mild mottle virus (BrMMV) and 66.7 to 68.7% identity with other tobamoviruses naturally infecting members of the Solanaceae plant family. Phylogenetic analysis of the complete genome nucleotide sequence and the deduced amino acid sequences of the four tobamovirus proteins place BrLV in a subcluster with BrMMV within the Solanaceae-infecting tobamovirus subgroup as a new species.

MeSH terms

  • Base Sequence
  • Brugmansia / virology*
  • Capsid Proteins / genetics*
  • Conserved Sequence
  • Genome, Viral*
  • Methyltransferases / genetics
  • Open Reading Frames
  • Phylogeny
  • Plant Diseases / virology
  • RNA, Viral / genetics*
  • RNA-Dependent RNA Polymerase / genetics
  • Sequence Alignment
  • Tobamovirus / classification
  • Tobamovirus / genetics*
  • Tobamovirus / isolation & purification
  • United Kingdom
  • Whole Genome Sequencing

Substances

  • Capsid Proteins
  • RNA, Viral
  • Methyltransferases
  • RNA-Dependent RNA Polymerase