SARS-CoV-2 IgG seroprevalence in blood donors located in three different federal states, Germany, March to June 2020

Euro Surveill. 2020 Jul;25(28):2001285. doi: 10.2807/1560-7917.ES.2020.25.28.2001285.

Abstract

Most cases of coronavirus disease 2019 are mild or asymptomatic. Therefore, many cases remain unrecorded. We determined seroprevalence of IgG antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 3,186 regular blood donors in three German federal states between 9 March and 3 June 2020. The IgG seroprevalence was 0.91% (95% confidence interval (CI): 0.58-1.24) overall, ranging from 0.66% (95% CI: 0.13-1.19) in Hesse to 1.22% (95% CI: 0.33-2.10) in Lower-Saxony.

Keywords: COVID-19, anti-SARS-CoV-2 IgG seroprevalence in Germany; SARS-CoV-2.

MeSH terms

  • Betacoronavirus / immunology*
  • Blood Donors / statistics & numerical data*
  • COVID-19
  • Coronavirus Infections / blood
  • Coronavirus Infections / diagnosis
  • Coronavirus Infections / epidemiology
  • Coronavirus Infections / immunology*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Germany / epidemiology
  • Humans
  • Immunoglobulin G / blood*
  • Male
  • Pandemics
  • Pneumonia, Viral / blood
  • Pneumonia, Viral / diagnosis
  • Pneumonia, Viral / epidemiology
  • Pneumonia, Viral / immunology*
  • SARS-CoV-2
  • Seroepidemiologic Studies
  • Spike Glycoprotein, Coronavirus / immunology
  • Time Factors

Substances

  • Immunoglobulin G
  • Spike Glycoprotein, Coronavirus
  • spike protein, SARS-CoV-2