Variant signaling topology at the cancer cell-T-cell interface induced by a two-component T-cell engager

Cell Mol Immunol. 2021 Jun;18(6):1568-1570. doi: 10.1038/s41423-020-0507-7. Epub 2020 Jul 24.

Authors

Dina Kouhestani¹, Maria Geis¹, Saed Alsouri¹, Thomas G P Bumm¹, Hermann Einsele¹, Markus Sauer², Gernot Stuhler³

Affiliations

¹ Department of Internal Medicine II, Hematology and Oncology, University Clinic Würzburg, Würzburg, Germany.
² Department of Biotechnology and Biophysics, University Würzburg, Würzburg, Germany.
³ Department of Internal Medicine II, Hematology and Oncology, University Clinic Würzburg, Würzburg, Germany. stuhler_g@ukw.de.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Antibodies, Bispecific / immunology
Antigens, Neoplasm / immunology
Cell Membrane / metabolism*
Humans
Immunological Synapses / metabolism
Jurkat Cells
Lymphocyte Activation / immunology
Neoplasms / immunology*
Neoplasms / pathology
Signal Transduction*
T-Lymphocytes / immunology*
THP-1 Cells

Substances

Antibodies, Bispecific
Antigens, Neoplasm