Management of Parkinson's disease and other movement disorders in woman of childbearing age: Part 1
Neurologia (Engl Ed). 2021 Mar;36(2):149-158.
doi: 10.1016/j.nrl.2020.05.010.
Epub 2020 Jul 24.
[Article in
English,
Spanish]
Authors
R García-Ramos
1
, D Santos-García
2
, A Alonso-Cánovas
3
, M Álvarez-Sauco
4
, B Ares
5
, A Ávila
6
, N Caballol
7
, F Carrillo
8
, F Escamilla Sevilla
9
, E Freire
10
, J C Gómez Esteban
11
, I Legarda
12
, L López Manzanares
13
, E López Valdés
14
, I Martínez-Torres
15
, M Mata
16
, I Pareés
17
, B Pascual-Sedano
18
, P Mir
8
, J C Martínez Castrillo
3
Affiliations
- 1 Hospital Clínico San Carlos, Madrid, España. Electronic address: garciaramosg@gmail.com.
- 2 CHUAC (Complejo Hospitalario Universitario de A Coruña), A Coruña, España.
- 3 Hospital Universitario Ramón y Cajal, Madrid, España.
- 4 Hospital General Universitario de Elche, Alicante, España.
- 5 Hospital Universitario de Santiago de Compostela, Santiago de Compostela, España.
- 6 Hospital General de l'Hospitalet, Consorci Sanitari Integral, L'Hospitalet de Llobregat, Barcelona, España; Hospital Sant Joan Despí Moisés Broggi, Consorci Sanitari Integral, Barcelona, España.
- 7 Hospital Sant Joan Despí Moisés Broggi, Consorci Sanitari Integral, Barcelona, España.
- 8 Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla. Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, España.
- 9 Hospital Universitario Virgen de las Nieves. Instituto de Investigación Biosanitaria ibs, Granada, España.
- 10 Hospital General Universitario de Elche, Alicante, España; Hospital IMED Elche, Elche, Alicante, España.
- 11 Hospital Universitario de Cruces, Bilbao, España.
- 12 Hospital Universitario Son Espases, Palma de Mallorca, España.
- 13 Hospital Universitario La Princesa, Madrid, España.
- 14 Hospital Clínico San Carlos, Madrid, España.
- 15 Hospital Universitario La Fe, Valencia, España.
- 16 Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, España.
- 17 Hospital Universitario Ramón y Cajal, Madrid, España; Hospital Ruber Internacional, Madrid, España.
- 18 Hospital Santa Creu i Sant Pau, Estudios de Ciencias de la Salud, Universitat Oberta de Catalunya (UOC), Barcelona, España.
Abstract
Introduction:
The main challenge of Parkinson's disease in women of childbearing age is managing symptoms and drugs during pregnancy and breastfeeding. The increase in the age at which women are having children makes it likely that these pregnancies will become more common in future.
Objectives:
This study aims to define the clinical characteristics of women of childbearing age with Parkinson's disease and the factors affecting their lives, and to establish a series of guidelines for managing pregnancy in these patients.
Results:
This consensus document was developed through an exhaustive literature search and a discussion of the available evidence by a group of movement disorder experts from the Spanish Society of Neurology.
Conclusions:
Parkinson's disease affects all aspects of sexual and reproductive health in women of childbearing age. Pregnancy should be well planned to minimise teratogenic risk. A multidisciplinary approach should be adopted in the management of these patients in order to take all relevant considerations into account.
Keywords:
Breastfeeding; Embarazo; Enfermedad de Parkinson; Lactancia; Levodopa; Parkinson's disease; Pregnancy; Reproductive health; Salud reproductiva.
Copyright © 2020 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.
MeSH terms
-
Adolescent
-
Adult
-
Consensus
-
Female
-
Humans
-
Neurology
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Parkinson Disease* / drug therapy
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Young Adult