Management of Parkinson's disease and other movement disorders in woman of childbearing age: Part 1

Neurologia (Engl Ed). 2021 Mar;36(2):149-158. doi: 10.1016/j.nrl.2020.05.010. Epub 2020 Jul 24.
[Article in English, Spanish]

Abstract

Introduction: The main challenge of Parkinson's disease in women of childbearing age is managing symptoms and drugs during pregnancy and breastfeeding. The increase in the age at which women are having children makes it likely that these pregnancies will become more common in future.

Objectives: This study aims to define the clinical characteristics of women of childbearing age with Parkinson's disease and the factors affecting their lives, and to establish a series of guidelines for managing pregnancy in these patients.

Results: This consensus document was developed through an exhaustive literature search and a discussion of the available evidence by a group of movement disorder experts from the Spanish Society of Neurology.

Conclusions: Parkinson's disease affects all aspects of sexual and reproductive health in women of childbearing age. Pregnancy should be well planned to minimise teratogenic risk. A multidisciplinary approach should be adopted in the management of these patients in order to take all relevant considerations into account.

Keywords: Breastfeeding; Embarazo; Enfermedad de Parkinson; Lactancia; Levodopa; Parkinson's disease; Pregnancy; Reproductive health; Salud reproductiva.

Publication types

  • Practice Guideline

MeSH terms

  • Adolescent
  • Adult
  • Consensus
  • Female
  • Humans
  • Neurology
  • Parkinson Disease* / drug therapy
  • Young Adult