[Raynaud phenomenon with arterial thromboses and IgG4-related disease]

T Lenfant; J Moroch; T de Risi-Pugliese; J-B Monfort; M Benjoar; A Barbaud; P Senet

doi:10.1016/j.revmed.2020.05.008

[Raynaud phenomenon with arterial thromboses and IgG4-related disease]

Rev Med Interne. 2020 Oct;41(10):708-713. doi: 10.1016/j.revmed.2020.05.008. Epub 2020 Jul 27.

[Article in French]

Authors

T Lenfant¹, J Moroch², T de Risi-Pugliese¹, J-B Monfort¹, M Benjoar³, A Barbaud¹, P Senet⁴

Affiliations

¹ Service de Dermatologie et Allergologie, Hôpital Tenon, AP-HP, Sorbonne Université, 4 rue de la Chine, 75020 Paris, France.
² Service d'Anatomopathologie, Hôpital Tenon, AP-HP, Sorbonne Université, 4 rue de la Chine, 75020 Paris, France.
³ Centre d'Imagerie Manin Crimée, 92 bis Rue de Crimée, 75019 Paris, France.
⁴ Service de Dermatologie et Allergologie, Hôpital Tenon, AP-HP, Sorbonne Université, 4 rue de la Chine, 75020 Paris, France. Electronic address: patricia.senet@aphp.fr.

PMID: 32727696
DOI: 10.1016/j.revmed.2020.05.008

Abstract

Introduction: This is a clinical case illustrating a diagnosis of an IgG4 related-disease (IgG4-RD) diagnosed in a vascular context.

Case report: A 47-year-old man with no past medical history consulted for a recent and disabling Raynaud phenomenon without trophic disorder. Vascular examinations revealed multiple arterial thromboses with no abnormal finger and toe pressures. Secondly, weight loss and submandibular glands enlargement appeared, leading to the diagnosis of IgG4-RD without a link being able to be established with vascular involvement. This is the second observation of this association. A French translation of the new classification criteria for IgG4-RD published in 2019 by the American College of Rheumatology and European Ligue Against Rhumatism (ACR/EULAR) is offered with direct application to the clinical case.

Conclusion: A Raynaud phenomenon with distal arterial thrombosis is rarely observed in the IgG4-RD.

Keywords: ACR; Acrosyndrome; Arterial thrombosis; IgG4; Phénomène de Raynaud; Raynaud phenomenon; Thromboses artérielles.

Publication types

Case Reports

MeSH terms

France
Humans
Immunoglobulin G4-Related Disease / complications
Immunoglobulin G4-Related Disease / diagnosis*
Male
Middle Aged
Radial Artery / diagnostic imaging
Radial Artery / pathology
Raynaud Disease / complications
Raynaud Disease / diagnosis*
Salivary Gland Diseases / complications
Salivary Gland Diseases / diagnosis
Salivary Gland Diseases / pathology
Thrombosis / complications
Thrombosis / diagnosis*
Thrombosis / pathology
Tobacco Smoking / pathology
Ulnar Artery / diagnostic imaging
Ulnar Artery / pathology