Revisiting the Resolution of Chiari Malformation in Nonsyndromic Craniosynostosis: A Case of Posterior Cranial Vault Reconstruction in Secondary Pan-Suture Synostosis

World Neurosurg. 2020 Nov:143:158-162. doi: 10.1016/j.wneu.2020.07.138. Epub 2020 Jul 27.

Abstract

Background: While commonly seen in syndromic craniosynostosis, the incidence of Chiari malformation (CM) in nonsyndromic craniosynostosis has been reported at 5% and there is a lack of understanding of the pathophysiology and management of CM in this patient population.

Case description: We present a 5-year-old male patient who underwent a sagittal craniosynostosis repair at the age of 5 months and returned at the age of 5 years with daily headaches associated with behavioral changes. He was found to have pan-synostoses and radiographic evidence of increased intracranial pressure, including a Chiari malformation. Neurologic and genetic workup was unremarkable. A cranial vault reconstruction was performed, and subsequent imaging demonstrated resolution of previously noted Chiari malformation.

Conclusions: In our case, we provided a unique window into the underlying pathophysiology for CM in patients with concurrent nonsyndromic craniosynostosis that we hope will add to the current foundation of literature supporting the intricate relation between cranial vault compliance and Chiari malformation or hindbrain herniation. Furthermore, we provide insight into the management of acquired CM and support isolated cranial vault reconstruction in those who do not appear to have symptomatic suboccipital compression.

Keywords: Chiari malformation; Cranial vault reconstruction; Nonsyndromic craniosynostosis.

Publication types

  • Case Reports

MeSH terms

  • Arnold-Chiari Malformation / etiology
  • Arnold-Chiari Malformation / psychology
  • Arnold-Chiari Malformation / surgery*
  • Child Behavior Disorders / etiology
  • Child Behavior Disorders / psychology
  • Child, Preschool
  • Craniosynostoses / complications
  • Craniosynostoses / psychology
  • Craniosynostoses / surgery*
  • Headache / etiology
  • Humans
  • Intracranial Pressure
  • Magnetic Resonance Imaging
  • Male
  • Neurosurgical Procedures / methods*
  • Plastic Surgery Procedures / methods*
  • Skull / surgery*
  • Tomography, X-Ray Computed
  • Treatment Outcome