Body weight is negatively associated with direct oral anticoagulant trough concentrations in dabigatran and apixaban users

Br J Haematol. 2020 Dec;191(5):941-944. doi: 10.1111/bjh.17009. Epub 2020 Aug 1.

Jacqueline M Borst^{1

2}, Nienke van Rein^{2

3

4}, Emilie C M D Bakker², Nikola Vukadin², Mike Rier⁵, Albert T A Mairuhu⁶, Francisca Hudig⁷, Liesbeth B E Bosma², Erik B Wilms^{2

8}, Loes E Visser^{2

9}

¹ Department of Hospital Care, Lairesse Pharmacy, Amsterdam, the Netherlands.
² Department of Hospital Pharmacy, Haga Teaching Hospital, The Hague, the Netherlands.
³ Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, the Netherlands.
⁴ Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
⁵ Department of Cardiology, Haga Teaching Hospital, The Hague, the Netherlands.
⁶ Department of Internal Medicine, Haga Teaching Hospital, The Hague, the Netherlands.
⁷ Department of Clinical Chemistry, Haga Teaching Hospital, The Hague, the Netherlands.
⁸ Laboratory, Central Hospital Pharmacy, The Hague, the Netherlands.
⁹ Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands.

No abstract available

Keywords: apixaban; dabigatran; edoxaban; rivaroxaban and body weight.

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