Should I Stay or Should I Go: eIF3 Remains Ribosome Associated and Is Required for Elongation

Tuija Pöyry; Mark Stoneley; Anne E Willis

doi:10.1016/j.molcel.2020.07.025

Should I Stay or Should I Go: eIF3 Remains Ribosome Associated and Is Required for Elongation

Mol Cell. 2020 Aug 20;79(4):539-541. doi: 10.1016/j.molcel.2020.07.025.

Authors

Tuija Pöyry¹, Mark Stoneley², Anne E Willis³

Affiliations

¹ MRC Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Rd, Cambridge CB2 1QW, UK. Electronic address: taap2@cam.ac.uk.
² MRC Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Rd, Cambridge CB2 1QW, UK.
³ MRC Toxicology Unit, University of Cambridge, Gleeson Building, Tennis Court Rd, Cambridge CB2 1QW, UK. Electronic address: aew80@cam.ac.uk.

PMID: 32822578
DOI: 10.1016/j.molcel.2020.07.025

Abstract

Wagner et al. (2020), Bohlen et al. (2020), and Lin et al. (2020) use Sel-TCP-seq or selective ribosome profiling to gain insights into mRNA translation initiation, highlighting distinctions between yeast and higher eukaryotes and a role for eIF3 in elongation.

Publication types

Comment

MeSH terms

Eukaryotic Initiation Factor-3*
Peptide Chain Initiation, Translational
Ribosomes*
Saccharomyces cerevisiae

Substances

Eukaryotic Initiation Factor-3

Abstract

Publication types

MeSH terms

Substances

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