Severe hypophosphataemia induced by glucose-insulin-potassium therapy. A case report and proposal for altered protocol

Int J Cardiol. 1988 Mar;18(3):327-30. doi: 10.1016/0167-5273(88)90051-4.

Abstract

A case is described where severe hypophosphataemia was induced by a widely used protocol for glucose-insulin-potassium (GIK) infusion. Hypophosphataemia was found to be a universal sequel to the use of this infusion. A new regimen for administering this agent was designed, and shown to lack the potentially serious side effect of phosphate depletion.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Coronary Disease / blood
  • Coronary Disease / therapy*
  • Glucose / administration & dosage
  • Glucose / adverse effects
  • Humans
  • Insulin / administration & dosage
  • Insulin / adverse effects
  • Male
  • Myocardial Infarction / blood
  • Myocardial Infarction / therapy*
  • Phosphates / blood*
  • Potassium / administration & dosage
  • Potassium / adverse effects

Substances

  • Insulin
  • Phosphates
  • glucose-insulin-potassium cardioplegic solution
  • Glucose
  • Potassium