Diastereoselective peroxidation of derivatives of Baylis-Hillman adducts

Tetrahedron. 2019 Aug 2;75(31):4118-4129. doi: 10.1016/j.tet.2019.05.008. Epub 2019 May 9.

Abstract

Cyclic derivatives of Baylis-Hillman adducts were synthesized. Cobalt-catalyzed peroxidation of these cyclic lactones afforded silyl peroxides in diastereomeric ratios ranging from 91:9 to 97:3.