Myocarditis in Multisystem Inflammatory Syndrome in Children Associated With Coronavirus Disease 2019

Cardiol Rev. 2020 Nov/Dec;28(6):308-311. doi: 10.1097/CRD.0000000000000341.

Abstract

Cardiac involvement as a complication of severe acute respiratory syndrome coronavirus 2 infection in children is a relatively new entity. We present our initial experience managing children with coronavirus disease 2019-related acute myocardial injury. The 3 patients presented here represent a spectrum of the cardiac involvement noted in children with coronavirus disease 2019-related multisystem inflammatory syndrome, including myocarditis presenting as cardiogenic shock or heart failure with biventricular dysfunction, valvulitis, coronary artery changes, and pericardial effusion.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Betacoronavirus* / isolation & purification
  • Betacoronavirus* / pathogenicity
  • COVID-19
  • Cardiac Imaging Techniques / methods
  • Child
  • Child, Preschool
  • Coronary Vessels / diagnostic imaging
  • Coronary Vessels / pathology
  • Coronavirus Infections* / diagnosis
  • Coronavirus Infections* / physiopathology
  • Coronavirus Infections* / therapy
  • Heart Failure* / etiology
  • Heart Failure* / therapy
  • Heart Valve Diseases* / diagnosis
  • Heart Valve Diseases* / virology
  • Humans
  • Myocarditis* / therapy
  • Myocarditis* / virology
  • Pandemics*
  • Patient Care Management / methods*
  • Pericardial Effusion* / therapy
  • Pericardial Effusion* / virology
  • Pneumonia, Viral* / diagnosis
  • Pneumonia, Viral* / physiopathology
  • Pneumonia, Viral* / therapy
  • SARS-CoV-2
  • Shock, Cardiogenic / etiology
  • Shock, Cardiogenic / therapy
  • Systemic Inflammatory Response Syndrome* / diagnosis
  • Systemic Inflammatory Response Syndrome* / physiopathology
  • Systemic Inflammatory Response Syndrome* / therapy
  • Treatment Outcome

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related