Review of Vitreopapillary Traction Syndrome

Rami S Gabriel; Chantal J Boisvert; Mitul C Mehta

doi:10.1080/01658107.2020.1725063

Review of Vitreopapillary Traction Syndrome

Neuroophthalmology. 2020 Feb 26;44(4):213-218. doi: 10.1080/01658107.2020.1725063. eCollection 2020.

Authors

Rami S Gabriel¹, Chantal J Boisvert², Mitul C Mehta³

Affiliations

¹ School of Medicine, University of California, Irvine, California, USA.
² Department of Ophthalmology, Duke Eye Center and Duke University Medical Center, Durham, North Carolina, USA.
³ Gavin Herbert Eye Institute, University of California, Irvine, California, USA.

Abstract

Vitreopapillary traction (VPT) syndrome is a potentially visually significant disorder of the vitreopapillary interface characterised by an incomplete posterior vitreous detachment with the persistently adherent vitreous exerting tractional pull on the optic disc and resulting in morphologic alterations and a consequent decline of visual function. It is most commonly unilateral but bilateral reports have also been described. The cause of the condition may be unknown or idiopathic, although the histology of traction shows proliferation of fibrous astrocytes, myofibroblasts, fibrocytes, and retinal pigment epithelial cells. It is theorised that VPT may induce a congested optic disc with neuronal dysfunction as well as decreased prelaminar flow. The present study reviews and summarises the features, diagnosis, and management of VPT.

Keywords: Vitreopapillary traction; optic disc; optic neuropathy; posterior vitreous detachment; visual field loss.

Publication types

Review

Grants and funding

This research was supported by Discovery Eye Foundation and an unrestricted grant from Research to Prevent Blindness Foundation. The sponsors had no role in the design, conduct, or decision to publish the research, nor did they have any role in the review or approval of the manuscript.