A routine third trimester growth ultrasound in the obese pregnant woman does not reliably identify fetal growth abnormalities: A retrospective cohort study

Aust N Z J Obstet Gynaecol. 2021 Feb;61(1):116-122. doi: 10.1111/ajo.13256. Epub 2020 Oct 24.

Abstract

Background: In response to the challenges of assessing fetal growth in obese women, guidelines recommend routine third trimester ultrasound scans.

Aim: The aim of this study was to assess the diagnostic performance of this routine scan in obese women (body mass index (BMI) ≥ 35 kg/m2 ).

Methods: A retrospective cohort study of 1008 pregnancies with maternal BMI ≥ 35 kg/m2 born after 37 weeks gestation at a Victorian hospital from 2015 to 2017. Multiple pregnancies and those affected by diabetes were excluded. Growth ultrasounds were performed between 34 + 0 and 36 + 6 weeks gestation. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) for the detection of large for gestational age (LGA > 90%) and small for gestational age (SGA < 10%) were calculated using ultrasound estimated fetal weight (EFW) or abdominal circumference (AC) and compared with gestational age and gender-based birthweight percentiles.

Results: Using EFW, sensitivity for detecting SGA at birth was 8.1% (six of 74) with a PPV of 100%. Sensitivity for detecting LGA at birth was 61.0% (119 of 195), PPV 54.8%. Sensitivity, specificity, PPV and NPV percentages were all lower using AC. Only 40% of actual birthweight percentiles (405/1008) were within ±10 percentiles of their growth ultrasound EFW percentile.

Conclusion: The performance of a routine third trimester ultrasound in women with BMI ≥ 35 kg/m2 suggests limited utility in helping identify aberrant fetal growth. This has important implications for the management of obese pregnant women.

Keywords: birthweight percentile; estimated fetal weight; obesity; sensitivity; ultrasound.

MeSH terms

  • Birth Weight
  • Female
  • Fetal Development
  • Fetal Growth Retardation / diagnostic imaging
  • Fetal Weight
  • Gestational Age
  • Humans
  • Infant, Newborn
  • Infant, Small for Gestational Age
  • Obesity / complications
  • Pregnancy
  • Pregnancy Trimester, Third
  • Pregnant People*
  • Retrospective Studies
  • Ultrasonography, Prenatal*