Lung volume reduction and infection localization revealed in Big data CT imaging of COVID-19

Int J Infect Dis. 2021 Jan:102:316-318. doi: 10.1016/j.ijid.2020.10.095. Epub 2020 Nov 3.

Abstract

The ongoing worldwide COVID-19 pandemic has become a huge threat to global public health. Using CT image, 3389 COVID-19 patients, 1593 community-acquired pneumonia (CAP) patients, and 1707 nonpneumonia subjects were included to explore the different patterns of lung and lung infection. We found that COVID-19 patients have a significant reduced lung volume with increased density and mass, and the infections tend to present as bilateral lower lobes. The findings provide imaging evidence to improve our understanding of COVID-19.

Keywords: Big data; COVID-19; Community-Acquired pneumonia; Lung; Non-Pneumonia subjects.

MeSH terms

  • Big Data
  • COVID-19 / diagnostic imaging*
  • COVID-19 / physiopathology
  • COVID-19 / virology
  • Community-Acquired Infections / diagnostic imaging
  • Community-Acquired Infections / physiopathology
  • Community-Acquired Infections / virology
  • Female
  • Humans
  • Lung / diagnostic imaging
  • Lung / physiopathology*
  • Lung / virology
  • Male
  • Middle Aged
  • Pandemics
  • Respiratory Function Tests
  • Retrospective Studies
  • SARS-CoV-2 / physiology
  • Tomography, X-Ray Computed / methods