Impact of an opioid stewardship program on opioid exposure for pediatric appendectomy postsurgical pain

J Pediatr Surg. 2021 Aug;56(8):1421-1424. doi: 10.1016/j.jpedsurg.2020.09.067. Epub 2020 Oct 18.

Abstract

Background/purpose: This study aimed to evaluate the impact of a Pediatric Acute Pain Guideline on postsurgical pain scores, opioid exposure, and discharge opioid prescribing habits in postappendectomy patients.

Methods: This was a retrospective single-center quality improvement project, including patients admitted for an appendectomy at a pediatric medical center between April 1 and December 31, 2018. Patients 0-17 years of age, who underwent a laparoscopic appendectomy without complications, were inpatient for at least 1 calendar day, and designated as presurgical American Society of Anesthesiologists (ASA) category 1 or 2 were included.

Results: Two hundred fifty-eight patients met inclusion criteria (n = 92 pre-, n = 166 post-guideline implementation). There was a decrease in the number of as needed opioid doses used (p = 0.014) and length of hospitalization (p = 0.003) post-guideline implementation compared to pre-guideline implementation. A decrease in the number of as needed doses of opioids used (p < 0.001) and in opioid exposure (p = 0.038) during hospitalization was also seen when the nonopioid pain agent was scheduled.

Conclusions: The implementation of the Pediatric Acute Pain Guideline was associated with a decrease in the number of as needed opioid doses used during hospitalization, which may have contributed to a decreased length of hospitalization. Scheduling nonopioid pain medications decreased opioid exposure.

Level of evidence: Treatment study level III.

Keywords: Appendectomy; Opioid crisis; Opioid stewardship; Pediatric acute pain guideline.

MeSH terms

  • Analgesics, Opioid* / therapeutic use
  • Appendectomy*
  • Child
  • Humans
  • Pain, Postoperative / drug therapy
  • Practice Patterns, Physicians'
  • Retrospective Studies

Substances

  • Analgesics, Opioid