Diagnostic Tests Can Stem the Threat of Antimicrobial Resistance: Infectious Disease Professionals Can Help

Clin Infect Dis. 2021 Jun 1;72(11):e893-e900. doi: 10.1093/cid/ciaa1527.

Abstract

Uptake of existing diagnostics to identify infections more accurately could minimize unnecessary antibiotic use and decrease the growing threat of antibiotic resistance. The Infectious Diseases Society of America (IDSA) and the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria (PACCARB) agree that, to improve uptake of existing diagnostics, healthcare providers, health systems, and payors all need better clinical and economic outcomes data to support use of diagnostic tests over empiric use of antibiotics, providers need better tools and education about diagnostic tests, and diagnostics developers need federal funding in the absence of a viable diagnostics market. Recommendations from PACCARB and the IDSA are amplified. Incentives for-and challenges to-diagnostics research, development, and uptake are summarized. Advocacy opportunities are given for infectious disease professionals to join the fight against antimicrobial resistance.

Keywords: Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria; antimicrobial resistance; diagnostics; outcomes research.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents* / therapeutic use
  • Bacteria
  • Communicable Diseases* / drug therapy
  • Diagnostic Tests, Routine
  • Drug Resistance, Bacterial
  • Humans

Substances

  • Anti-Bacterial Agents