1 Jonathan King is with the Department of Biology, Massachusetts Institute of Technology, Cambridge. David Goldenberg is with the Department of Biology, University of Utah, Salt Lake City. Gary Goldstein is with the Department of Physics, Tufts University, Medford, MA. William Hartung is with the Center for International Policy, Washington, DC. Catherine Royer is with the Department of Chemistry, Renssalaer Polytechnic Institute, Troy, NY. Eric Sundberg is with the Department of Biochemistry, Emory University School of Medicine, Atlanta, GA. Cornelia van der Ziel is unaffiliated. Michael Van Elzakker is with the Department of Neuroscience, Mass General Hospital, Boston, MA. Sir Richard Roberts is with New England Biolabs Inc., Ipswich, MA.