Cost-Effectiveness of Treatments after Closed Extraarticular Distal Radius Fractures in Older Adults from the WRIST Clinical Trial

Plast Reconstr Surg. 2021 Feb 1;147(2):240e-252e. doi: 10.1097/PRS.0000000000007528.

Abstract

Background: This study performs an economic analysis of volar locking plate, external fixation, percutaneous pinning, or casting in elderly patients with closed distal radius fractures.

Methods: This is a secondary analysis of the Wrist and Radius Injury Surgical Trial, a randomized, multicenter, international clinical trial with a parallel nonoperative casted group of patients older than 60 years with surgically indicated, extraarticular closed distal radius fractures. Thirty-Six-Item Short-Form Health Survey-converted utilities and total costs from Medicare were used to calculate quality-adjusted life-years and incremental cost-effectiveness ratio.

Results: Casted patients were self-selected and older (p < 0.001) than the randomized surgical cohorts, but otherwise similar in sociodemographic characteristics. Quality-adjusted life-years for percutaneous pinning were highest at 9.17 and external fixation lowest at 8.81. Total costs expended were $16,354 for volar locking plates, $16,012 for external fixation, $11,329 for percutaneous pinning, and $6837 for casting. The incremental cost-effectiveness ratios for volar locking plates and external fixation were dominated by percutaneous pinning and casting. The ratio for percutaneous pinning compared to casting was $28,717. Probabilistic sensitivity analysis revealed a 10, 5, 53, and 32 percent chance of volar locking plate, external fixation, percutaneous pinning, and casting, respectively, being cost-effective at the willingness-to-pay threshold of $100,000 per quality-adjusted life-year.

Conclusions: Casting is the most cost-effective treatment modality in the elderly with closed extraarticular distal radius fractures and should be considered before surgery. In unstable closed fractures, percutaneous pinning, which is the most cost-effective surgical intervention, may be considered before volar locking plates or external fixation.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Bone Plates / economics
  • Bone Plates / statistics & numerical data
  • Casts, Surgical / economics
  • Casts, Surgical / statistics & numerical data
  • Cost-Benefit Analysis
  • Female
  • Fracture Fixation, Internal / adverse effects
  • Fracture Fixation, Internal / economics*
  • Fracture Fixation, Internal / instrumentation
  • Fracture Fixation, Internal / methods
  • Health Care Costs / statistics & numerical data*
  • Humans
  • Male
  • Middle Aged
  • Models, Economic
  • Postoperative Complications / economics
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / etiology
  • Quality-Adjusted Life Years
  • Radius Fractures / complications
  • Radius Fractures / economics
  • Radius Fractures / surgery*
  • Treatment Outcome
  • United States
  • Wrist Injuries / complications
  • Wrist Injuries / economics
  • Wrist Injuries / surgery*