Methylphenidate-Induced Enuresis: 3 Case Reports

Necati Uzun; Mehmet Akif Akinci; Serdar Karatoprak

doi:10.1097/WNF.0000000000000422

Methylphenidate-Induced Enuresis: 3 Case Reports

Clin Neuropharmacol. 2021 Jan-Feb;44(1):37-38. doi: 10.1097/WNF.0000000000000422.

Authors

Necati Uzun¹, Mehmet Akif Akinci², Serdar Karatoprak³

Affiliations

¹ Department of Child and Adolescent Psychiatry, Necmettin Erbakan University Meram School of Medicine.
² Department of Child and Adolescent Psychiatry, Dr. Ali Kemal Belviranli Maternity and Children Hospital.
³ Department of Child and Adolescent Psychiatry, Konya Training and Research Hospital, Konya, Turkey.

PMID: 33252370
DOI: 10.1097/WNF.0000000000000422

Abstract

Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents. Methylphenidate (MPH) is one of the most widely used drugs in the treatment of ADHD. Enuresis can occur comorbidly with ADHD. However, enuresis is sometimes seen in patients with ADHD as an adverse effect of MPH treatment. In contrast, in some cases, MPH reportedly improves enuresis in patients with ADHD comorbid with enuresis. The literature is contradictory with regard to the relationship between MPH and enuresis. This report presents the cases of 3 children with ADHD who displayed enuresis during MPH treatment.

Publication types

Case Reports

MeSH terms

Attention Deficit Disorder with Hyperactivity / diagnosis
Attention Deficit Disorder with Hyperactivity / drug therapy
Central Nervous System Stimulants / adverse effects*
Child
Humans
Male
Methylphenidate / adverse effects*
Nocturnal Enuresis / chemically induced*
Nocturnal Enuresis / diagnosis*

Substances

Central Nervous System Stimulants
Methylphenidate