Peri-ictal headaches in the paediatric population - prospective study

Cephalalgia. 2021 May;41(6):690-700. doi: 10.1177/0333102420977856. Epub 2020 Dec 9.

Abstract

Introduction: The co-occurrence of headache and epilepsy is well-documented in the adult population. The aim of the prospective study was to analyse in the paediatric population the correlations between the types of peri-ictal headaches and types of seizures. Furthermore, an attempt was made to find trends in characteristic features of peri-ictal headaches.Material: A total of 57 children with peri-ictal headache were enrolled in the study. The participants' guardians were asked to keep a diary of the seizure and peri-ictal headache episodes during a 180-day period. During follow-up visits, systematic history regarding peri-ictal headaches was taken.

Results: A total of 913 seizure and 325 peri-ictal headache episodes were noted during the study. Post-ictal headaches were most common, occurring in < 1 h after the seizure, lasting minutes to hours and more likely to occur after generalised seizures, whereas pre-ictal headaches occurred 30-240 min before the seizure. In the analysed group, peri-ictal headaches were most often moderate in intensity. Only 30% of patients took analgesic medication, usually to treat post-ictal headaches.

Conclusion: Peri-ictal headaches are a significant health problem for patients with epilepsy. The most common type are post-ictal headaches, and they are most likely to appear after a generalised seizure.

Keywords: Peri-ictal headache; characteristic; children.

MeSH terms

  • Adolescent
  • Child
  • Electroencephalography
  • Epilepsy / epidemiology*
  • Female
  • Headache / complications*
  • Headache / diagnosis
  • Headache / epidemiology
  • Humans
  • Male
  • Prevalence
  • Prospective Studies
  • Seizures / epidemiology*
  • Seizures / etiology*