Microbial Respiration in the Colon: Using H2O2 to Catch Your Breath

Shauna M Crowley; Bruce A Vallance

doi:10.1016/j.chom.2020.11.006

Microbial Respiration in the Colon: Using H₂O₂ to Catch Your Breath

Cell Host Microbe. 2020 Dec 9;28(6):771-773. doi: 10.1016/j.chom.2020.11.006.

Authors

Shauna M Crowley¹, Bruce A Vallance²

Affiliations

¹ Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada.
² Department of Pediatrics, BC Children's Hospital, University of British Columbia, Vancouver, BC, Canada. Electronic address: bvallance@cw.bc.ca.

PMID: 33301714
DOI: 10.1016/j.chom.2020.11.006

Abstract

To colonize the nutritionally competitive environment of the gut, invading bacteria must utilize unique metabolites. Two reports in this issue of Cell Host & Microbe describe how Citrobacter rodentium and Escherichia coli leverage colonocyte derived H₂O₂ to drive two distinct respiratory pathways that support their proliferation in the mouse intestine.

Publication types

Comment

MeSH terms

Animals
Citrobacter rodentium
Colon
Escherichia coli*
Hydrogen Peroxide*
Inflammation
Mice
Reactive Oxygen Species
Respiration
Soil Microbiology

Substances

Reactive Oxygen Species
Hydrogen Peroxide