Oral lichen planus and HCV infection

Jefferson R Tenório; Alessandra Rodrigues de Camargo; Celso Lemos; Karem L Ortega

doi:10.4322/acr.2020.210

Oral lichen planus and HCV infection

Autops Case Rep. 2020 Nov 20;10(4):e2020210. doi: 10.4322/acr.2020.210.

Authors

Jefferson R Tenório¹, Alessandra Rodrigues de Camargo², Celso Lemos³, Karem L Ortega¹

Affiliations

¹ Universidade de São Paulo (USP), Faculdade de Odontologia, Patologia Oral e Maxilofacial, Departamento de Estomatologia, São Paulo, SP, Brasil.
² Universidade Federal de Santa Catarina (UFSC), Departamento de Estomatologia, Florianópolis, SC, Brasil.
³ Universidade de São Paulo (USP), Faculdade de Odontologia, Departamento de Estomatologia, São Paulo, SP, Brasil.

Abstract

Chronic infection by hepatitis C virus (HCV) can lead not only to the development of hepatic cirrhosis, but also to the emergence of extra-hepatic manifestations (EHMs), such as oral lichen planus (OLP). Here, we describe a clinical presentation of massive, erosive OLP in an HCV-positive patient whose clinical management was difficult. Full remission was achieved after sustained virological response by using direct-acting anti-retrovirals. This case report demonstrates not only the importance of diagnosing EHMs for identification of HCV infection, but also the importance of controlling it for management of OLP and EHMs.

Keywords: Chronic; Hepatitis C; Lichen Planus, Oral.