The discovery of the HLA-B*56:75 allele shows that HLA sequencing is important in all transplant settings

HLA. 2021 May;97(5):463-464. doi: 10.1111/tan.14176. Epub 2021 Jan 7.

Authors

Justin C Quon¹, William D Lyle², Lee Ann Baxter-Lowe^{2

3}

Affiliations

¹ Keck School of Medicine, University of Southern California, California, Los Angeles, USA.
² Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, California, Los Angeles, USA.
³ Department of Pathology, Keck School of Medicine, University of Southern California, California, Los Angeles, USA.

PMID: 33369190
DOI: 10.1111/tan.14176

Abstract

HLA-B*56:75 has a nonsynonymous C to G substitution in codon 73 compared to HLA-B*56:01:01:02.

Keywords: HLA-B*56:75; HLA; next-generation sequencing; novel allele; transplantation.

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

MeSH terms

Alleles
Codon
Exons / genetics
HLA-B Antigens* / genetics
Humans
Sequence Analysis, DNA

Substances

Codon
HLA-B Antigens
HLA-B56 antigen