Epidemiology of non-IgE-mediated food allergies: what can we learn from that?

Curr Opin Allergy Clin Immunol. 2021 Apr 1;21(2):188-194. doi: 10.1097/ACI.0000000000000721.

Abstract

Purpose of review: To underline the main characteristics of the non-Immunoglobulin E (IgE)-mediated food allergies (food protein-induced allergic proctocolitis food protein-induced enteropathy and food protein-induced enterocolitis syndrome ), which are common diseases in primary care and in allergy and gastroenterology specialty practices evaluating children.

Recent findings: Non-IgE-mediated food allergies comprise a spectrum of diseases with peculiar features affecting infants and young children. The most prominent features of these diseases are symptoms that affect mainly the gastrointestinal tract.

Summary: It is of paramount importance to provide the clinicians with the tools for non-IgE-mediated food allergy recognition in clinical practice to avoid the misdiagnosis with unnecessary laboratory tests and detrimental treatments.

Publication types

  • Review

MeSH terms

  • Child
  • Child, Preschool
  • Enterocolitis* / diagnosis
  • Enterocolitis* / epidemiology
  • Food Hypersensitivity* / diagnosis
  • Food Hypersensitivity* / epidemiology
  • Humans
  • Immunoglobulin E
  • Infant

Substances

  • Immunoglobulin E